ST Helens hooker Dom Speakman is set to make his debut as a replacement for the injured James Roby.
Captain Paul Wellens is fit again after a month’s absence with a calf injury but he is likely to return at loose forward, with Tom Makinson or Nathan Ashe taking the place of Jonny Lomax at full-back.
Saints are also boosted by the return from injury of front-row forwards Josh Perry and Tony Puletua.
It unlikely the severe weather will prevent the game going ahead, Saints say.
Salford are without three first-choice front-row forwards after Lee Jewitt (flu) and Vic Mauro (knee injury) joined Shannon McPherson on the sidelines.
Winger Danny Williams is back from a quad injury to take the place of loan signing Jack Murphy and utility back Ryan McGoldrick stands by to replace former St Helens centre Martin Gleeson if he fails to overcome a knee injury.