Corporation Street in St Helens has now re-opened to traffic near its junctions with Hall Street and Shaw Street at the Millennium Centre following a traffic incident earlier this morning.
The incident happened at around 10.30am today (Thursday).
A police spokesman said three vehicles - a Hackney taxi cab, a white Ford Fiesta and a red Citroen - were involved in the collision.
The Citroen was left on its side, trapping the driver and passengers.
Police and fire crews were dispatched to the scene, with officers closing Corporation Street at its junctions with Hall Street and Shaw Street near the Millennium Centre.
A number of people have been taken to hospital with minor injuries.